【2544】Time control is very important
Zhongshan Medical First Affiliated Hospital must have this technical strength, so they don’t need to fly over. The doctor who will be responsible for picking donors’ donors’ hearts during the operation is Dr. Ye Chuanguang.
"Does your doctor have any requirements for us?" Ye Chuanguang asked.
While Xie Wanying was talking on the phone, she pulled out the ballpoint pen in her hand.
Seeing this, Wei helped her take out her laptop and make it easier for her to write on the laptop.
Xie Wanying wrote that she wanted to coordinate with the other party and let Teacher Cheng take a look at the matters she wanted to coordinate with.
Dr. Cheng Yuchen nodded while watching.
After obtaining the teacher's consent, Xie Wanying said: "First of all, the distance for the heart to transport is relatively long, and some preparations require you, Teacher Ye, to cooperate with you."
"You're welcome." Ye Chuanguang said frankly, "If you don't call here, we would like to ask you what your plans are. Do we need to inject cardiac arrest fluid from the aorta root to store it?"
"Yes." A powerful teacher doesn't need to say anything more and understand it almost instantly.
"But you have to be clear that the time for heart cold ischemia should not exceed five or six hours." Ye Chuanguang nagged and reminded, don't think that doing more preparation steps can bring everything good, and it will be delayed at most.
Cold ischemia can be said to be a proper noun in organ transplant technology. Before talking about cold ischemia, another similar technical noun: hot ischemia.
The operation period before the organ is removed from the donor's heart and is taken down for cold preservation is called hot ischemia. Cold ischemia is corresponding to the time period when the organ leaves the donor and is transplanted into the recipient. The most important thing here is the transportation time on the road.
The heat ischemia and cold ischemia time of each organ is upper limit. For example, the upper limit of heart heat ischemia and cold ischemia is the shortest, ten minutes and eight hours respectively. The ten minutes and eight hours here are super upper limits, which is equivalent to a big adventure. No one can easily take this risk. Therefore, the cold ischemia time that Dr. Ye said is best not to exceed five or six hours. The time for the heat ischemia time of their hospital to collect the heart for donor will be controlled within five minutes.
What's going on injecting cardiac arrest fluid? Here we will talk about the cells that did not die when the organs were picked from the donor and continued to metabolize. Due to the interruption of blood flow and no blood nourishment, the organs taken out will inevitably suffer from self-consuming metabolic damage. It can be imagined that this period of heat ischemia damages the donor organs the most, and a skilled professional doctor is needed to do this to shorten the operation time as much as possible.
How to protect the heart in the cold ischemia stage? From a medical technology perspective, it is either the most ideal state, and use machinery to simulate the normal body to continuously inject the heart into the heart, so that the damage is minimal. The problem is that long-distance transportation cannot be done at all, so we can only wait a little longer. Use other methods to reduce the metabolism rate of the heart and reduce damage. Therefore, there must be low temperatures and other components in the general organ preservation fluid to inhibit organ cell metabolism.
The energy consumption of the heart is mainly composed of the movement of heart contraction and diastolic and cardiomyocyte metabolism. The former accounts for 90% of the total consumption. Using cardiac arrest fluid can stop cardiac mechanical activity, and low temperatures can reduce cardiomyocyte metabolism. The combination of the two is equal to one plus one, which doubles the effect of reducing loss.
Protecting the myocardium is one aspect.
Chapter completed!