【2648】market decision
Polyester is the first material used in the manufacturing of artificial blood vessels. Medical polyester is safe to stay in the human body as long as medical sutures. Its biggest problem is that it has poor anticoagulation, requires anticoagulation pretreatment, and needs to be coated with a biological coating.
ePTFE is an expanded body commonly known as the plastic king. It is equivalent to a new product made by special processes based on PTFE. In comparison, ePTFE performs very well in anticoagulation. It is also very biocompatible in the human body and has very light repulsion. It is also not easy to degrade as polyester, and can be used in the human body for a long time without frequent replacement. Compared with polyester, it does not require anticoagulation pretreatment or biological uncoated. These conveniences make it well received clinically.
Is the new generation of artificial vascular star materials really not at all disadvantages? There is no safe and perfect thing in the world. It is impossible for medical devices to achieve tissues and organs that grow on the human body.
The disadvantages of ePTFE have been summarized in the international research papers. They are always not as flexible as the human body's own blood vessels. Their softness is poorer than that of the human body, causing blood to flow inside for a long time. Over time, it is easier to form thrombus at the anastomosis and cause blockage.
Such instruments and materials are very challenging to the surgeon's technical level.
If a surgeon is skilled, he may be able to help the patient deal with the artificial vascular anastomosis better, and the probability of blockage is low, and even if it occurs, the time point will be delayed. If the surgeon's skill is average, the consequences needless to say.
Can all surgeons be required to achieve excellent skills?
Impossible. The supply and demand of particularly excellent surgeons have always been unbalanced.
For example, inventing a smartphone, it must have a fool-friendly operation method that most people can use. If it is made into a complex operation, only coders can use it, it will become something that is not for the public and cannot be sold.
In the medical materials market, it becomes: the medical surgical materials created must meet the technical level of most surgeons, rather than the technical level of big bulls.
If you simply use Daniu’s technical level to make medical equipment, it is destined to be unable to promote it, and even clinical trials cannot pass, because the results of the clinical trial will be so bad. For example, there is a clinical trial indicator for artificial blood vessels, called long-term vascular patency. Daniu’s surgery may make this material’s indicator perform well, reaching 80 to 90% in half a year, and surgeons with general technical level can only reach 40 to 50% without the qualification.
The test results should be based on surgeons of general technical level. Seeing this clinical trial value, all clinicians and researchers will have two large heads.
In summary, ePTFE has disadvantages, but since it has been recognized in artificial blood vessel production internationally, the same sentence, the proportion of bad ones should be controlled within a controllable range and should not exceed it.
Next, it can only become a problem of choosing one of two. Either is this material not good? Or is there an indescribable contradiction between this surgical technology and new products?
Chapter completed!